Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.66 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4224757 | 0.92 | CTSK (0.77) | CTSKCTSSDPP4DPP8DPP9 | |
| SCHEMBL4048538 | 0.92 | CTSK (0.77) | CTSKCTSSDPP4DPP8DPP9 | |
| SCHEMBL5941541 | 0.92 | CTSK (0.77) | CTSKCTSSDPP4DPP8DPP9 | |
| SCHEMBL4224752 | 0.92 | CTSK (0.77) | CTSKCTSSDPP4DPP8DPP9 | |
| SCHEMBL4043482 | 0.87 | CTSK (0.74) | CTSKCTSSMEN1ALDH1A1KMT2A | |
| SCHEMBL4037975 | 0.86 | CTSK (0.73) | CTSKCTSSDPP4CCR1 | |
| SCHEMBL4043175 | 0.86 | CTSK (0.73) | CTSKCTSSCCR1 | |
| SCHEMBL4044320 | 0.86 | CTSK (0.75) | CTSKCTSSMEN1ALDH1A1KMT2A | |
| SCHEMBL4046382 | 0.86 | CTSK (0.72) | CTSKCTSSDPP4CCR1 | |
| SCHEMBL4044162 | 0.84 | CTSK (0.75) | CTSKCTSSDPP4MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |