Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 8/20 | 0.48 |
| ▸ | MMP2 | P08253 | 7/20 | 0.48 |
| ▸ | MMP1 | P03956 | 6/20 | 0.48 |
| ▸ | MMP8 | P22894 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569855 | 0.86 | TRPV1 (0.50) | MMP9MMP2MMP1MMP8NAMPT | |
| SCHEMBL29338138 | 0.85 | MMP9 (0.53) | MMP9MMP2MMP1MMP8NAMPT | |
| SCHEMBL4861084 | 0.82 | MMP9 (0.51) | MMP9MMP2MMP1MMP8NAMPT | |
| SCHEMBL4859637 | 0.82 | MMP9 (0.51) | MMP9MMP2MMP1MMP8NAMPT | |
| SCHEMBL6418633 | 0.80 | MMP9 (0.51) | MMP9MMP2MMP1MMP8MAPT | |
| SCHEMBL6418630 | 0.80 | MMP9 (0.51) | MMP9MMP2MMP1MMP8MAPT | |
| SCHEMBL6418631 | 0.80 | MMP9 (0.51) | MMP9MMP2MMP1MMP8MAPT | |
| SCHEMBL23343881 | 0.79 | MMP9 (0.56) | MMP9MMP2MMP1MMP8NAMPT | |
| SCHEMBL1177439 | 0.79 | MMP9 (0.53) | MMP9MMP2MMP1MMP8NAMPT | |
| SCHEMBL4858952 | 0.79 | MMP9 (0.53) | MMP9MMP2MMP1MMP8NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003030886-A2 | ALLYLAMIDES USEFUL IN THE TREATMENT OF ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC (US) | 2003-04-17 | — | — | WO | disclosed |