Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.91 |
| ▸ | FBP1 | P09467 | 3/20 | 0.86 |
| ▸ | KDR | P35968 | 9/20 | 0.85 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.85 |
| ▸ | SRC | P12931 | 2/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.85 |
| ▸ | GAK | O14976 | 1/20 | 0.85 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.85 |
| ▸ | ABL1 | P00519 | 1/20 | 0.85 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.85 |
| ▸ | CDK1 | P06493 | 1/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.85 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.85 |
| ▸ | MAPT | P10636 | 1/20 | 0.85 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.85 |
| ▸ | TSHR | P16473 | 1/20 | 0.85 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.85 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.85 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.85 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5742396 | 0.94 | EGFR (0.86) | EGFRFBP1KDRERBB2SRC | |
| SCHEMBL22367416 | 0.93 | FBP1 (1.00) | EGFRFBP1KDRERBB2SRC | |
| SCHEMBL4232360 | 0.93 | FBP1 (0.84) | EGFRFBP1KDRERBB2SRC | |
| SCHEMBL12963484 | 0.92 | FBP1 (0.91) | EGFRFBP1KDRERBB2SRC | |
| SCHEMBL29444884 | 0.92 | EGFR (1.00) | EGFRFBP1KDRERBB2SRC | |
| SCHEMBL9423 | 0.92 | EGFR (1.00) | EGFRFBP1KDRERBB2SRC | |
| SCHEMBL30363011 | 0.92 | EGFR (1.00) | EGFRFBP1KDRERBB2SRC | |
| SCHEMBL28641557 | 0.92 | FBP1 (0.83) | EGFRFBP1KDRERBB2SRC | |
| Hydrochloric Acid SCHEMBL29369196 | 0.91 | EGFR (1.00) | EGFRFBP1KDRERBB2SRC | |
| Hydrochloric Acid SCHEMBL30362813 | 0.91 | EGFR (1.00) | EGFRFBP1KDRERBB2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003024448-A2 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2003-03-27 | — | — | WO | disclosed |