SCHEMBL8350165

SCHEMBL8350165

O=C1CCC2=C1CCCCC2

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 2/20 0.38
TRIM33 Q9UPN9 2/20 0.38
ALDH1A1 P00352 2/20 0.38
HSD17B10 Q99714 2/20 0.32
HPGD P15428 2/20 0.32
HTT P42858 1/20 0.32
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30
ALOX12 P18054 1/20 0.30
BLM P54132 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29540851 1.00 TRIM24 (0.38) TRIM24TRIM33ALDH1A1HSD17B10HPGD
SCHEMBL8070883 1.00 TRIM24 (0.38) TRIM24TRIM33ALDH1A1HSD17B10HPGD
SCHEMBL889421 0.97 TRIM24 (0.35) TRIM24TRIM33ALDH1A1HSD17B10
SCHEMBL131908 0.92 ALDH1A1 (0.40) TRIM24TRIM33ALDH1A1HSD17B10HPGD
SCHEMBL1338998 0.92
SCHEMBL8900690 0.89 ALDH1A1 (0.38) TRIM24TRIM33ALDH1A1HSD17B10HPGD
SCHEMBL5833660 0.89 ALDH1A1 (0.38) TRIM24TRIM33ALDH1A1HSD17B10HPGD
SCHEMBL6151244 0.89 ALDH1A1 (0.38) TRIM24TRIM33ALDH1A1HSD17B10HPGD
SCHEMBL6249725 0.88 TRIM24 (0.37) TRIM24TRIM33ALDH1A1HSD17B10HPGD
SCHEMBL5464779 0.86 TRIM24 (0.35) TRIM24TRIM33ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11639484-B2 Perfume compositions GIVAUDAN SA (CH) 2023-05-02 US disclosed
US-20170073614-A1 Perfume Compositions GIVAUDAN SA (CH) 2017-03-16 US disclosed
EP-0760355-B1 Process for the preparation of cyclopentadienyl derivatives ENICHEM SPA (IT) 1999-10-27 EP disclosed
US-5900517-A Cyclopentadienyl derivatives and process for their preparation ENICHEM S.P.A. (IT) 1999-05-04 US disclosed
EP-0760355-A1 Cyclopentadienyl derivatives and process for their preparation ENICHEM S.p.A. (IT) 1997-03-05 EP disclosed