Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13305065 | 0.84 | GPR52 (0.45) | GPR52SMN1; SMN2HPGDLMNAALDH1A1 | |
| SCHEMBL13305057 | 0.82 | GPR52 (0.44) | GPR52SMN1; SMN2HPGDLMNAALDH1A1 | |
| SCHEMBL11528932 | 0.80 | GPR52 (0.61) | GPR52SMN1; SMN2HPGDLMNAALDH1A1 | |
| SCHEMBL11528927 | 0.80 | GPR52 (0.61) | GPR52SMN1; SMN2HPGDLMNAALDH1A1 | |
| SCHEMBL6218684 | 0.80 | MEN1 (0.58) | GPR52SMN1; SMN2HPGDLMNAALDH1A1 | |
| SCHEMBL3311627 | 0.80 | GPR52 (0.49) | GPR52SMN1; SMN2HPGDLMNAALDH1A1 | |
| SCHEMBL29566671 | 0.80 | MEN1 (0.58) | GPR52SMN1; SMN2HPGDLMNAALDH1A1 | |
| SCHEMBL3311630 | 0.80 | GPR52 (0.49) | GPR52SMN1; SMN2HPGDLMNAALDH1A1 | |
| SCHEMBL3311666 | 0.80 | GPR52 (0.49) | GPR52SMN1; SMN2HPGDLMNAALDH1A1 | |
| SCHEMBL13183389 | 0.80 | GPR52 (0.42) | GPR52SMN1; SMN2HPGDLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010110400-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2010-09-30 | — | — | WO | disclosed |
| WO-2009101917-A1 | BICYCLOAMINE DERIVATIVE | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-08-20 | — | — | WO | disclosed |
| WO-2003030886-A2 | ALLYLAMIDES USEFUL IN THE TREATMENT OF ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC (US) | 2003-04-17 | — | — | WO | disclosed |