Sugi Predict

Sugi Predict / Compounds / SCHEMBL8350650

SCHEMBL8350650

SCHEMBL8350650

CCc1nc(SC)c(C(O)(C(=O)O)c2ccccc2)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)NCc2ccccc2)cc1

nearest known ligand 0.89

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ AGTR2 P50052 17/20 0.89
▸ AGTR1 P30556 3/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6545419 0.94 AGTR2 (1.00) AGTR2AGTR1
SCHEMBL8347071 0.86 AGTR2 (1.00) AGTR2AGTR1
SCHEMBL8348626 0.81 AGTR2 (0.72) AGTR2AGTR1
SCHEMBL8352504 0.81 AGTR2 (0.77) AGTR2AGTR1
SCHEMBL8345753 0.81 AGTR2 (0.72) AGTR2AGTR1
SCHEMBL6544946 0.80 AGTR2 (1.00) AGTR2AGTR1
SCHEMBL8347068 0.79 AGTR2 (0.81) AGTR2AGTR1
SCHEMBL8348141 0.79 AGTR2 (1.00) AGTR2AGTR1
SCHEMBL6545773 0.79 AGTR2 (1.00) AGTR2AGTR1
SCHEMBL7022990 0.78 AGTR2 (0.89) AGTR2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5977155-A CARDIOVASCULAR, KIDNEYS HOECHST MARION ROUSSEL (FR) 1999-11-02 — — US disclosed