Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16312309 | 0.84 | TSHR (0.59) | TSHRALDH1A1CYP3A4HTTGLA | |
| SCHEMBL3966075 | 0.84 | TSHR (0.59) | TSHRALDH1A1CYP3A4HTTGLA | |
| SCHEMBL8436255 | 0.83 | TSHR (0.36) | TSHRALDH1A1CYP3A4HTTGLA | |
| SCHEMBL1931195 | 0.82 | TSHR (0.57) | TSHRALDH1A1CYP3A4HTTGLA | |
| SCHEMBL2105851 | 0.82 | TSHR (0.57) | TSHRALDH1A1CYP3A4HTTGLA | |
| SCHEMBL18638052 | 0.82 | TSHR (0.57) | TSHRALDH1A1CYP3A4HTTGLA | |
| SCHEMBL16312317 | 0.82 | TSHR (0.57) | TSHRALDH1A1CYP3A4HTTGLA | |
| SCHEMBL5932194 | 0.82 | TSHR (0.57) | TSHRALDH1A1CYP3A4HTTGLA | |
| SCHEMBL11276095 | 0.81 | TSHR (0.52) | TSHRALDH1A1CYP3A4HTTGLA | |
| SCHEMBL19873329 | 0.81 | TSHR (0.55) | TSHRALDH1A1CYP3A4HTTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998082-A | DIHYDROCARBYLOXYPHENYL DIAZONIUM COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| US-5298539-A | Derivatives of melamine, acetoguanamine, benzoguanamine and glycouril groups with vinyl groups | CYTEC INDUSTRIES, INC. (US) | 1994-03-29 | — | — | US | disclosed |
| EP-0473948-A2 | Additives for improving tire cord adhesion and toughness of vulcanized rubber compositions | CYTEC TECHNOLOGY CORP. (US) | 1992-03-11 | — | — | EP | disclosed |