Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8350700 | 0.83 | TSHR (0.55) | TSHRHTTGLAL3MBTL1LMNA | |
| SCHEMBL8437414 | 0.78 | — | — | |
| SCHEMBL3274384 | 0.77 | TSHR (0.37) | TSHRUSP2HTTGLAL3MBTL1 | |
| SCHEMBL8436259 | 0.77 | MAPK1 (0.40) | TSHRUSP2HTTCYP2D6CYP2C19 | |
| SCHEMBL3274387 | 0.77 | CYP2D6 (0.56) | TSHRUSP2HTTGLAL3MBTL1 | |
| SCHEMBL8437855 | 0.76 | TSHR (0.33) | TSHRUSP2HTTGLAL3MBTL1 | |
| SCHEMBL17624747 | 0.75 | KMT2A (0.48) | TSHRUSP2HTTGLAL3MBTL1 | |
| SCHEMBL9749983 | 0.75 | BCAT2 (0.39) | TSHRUSP2HTTGLAL3MBTL1 | |
| SCHEMBL17183684 | 0.75 | TSHR (0.50) | TSHRUSP2HTTGLAL3MBTL1 | |
| SCHEMBL459003 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110088120-A | inhibitors of transglutaminase | 策迪拉有限公司 | 2019-08-02 | — | — | CN | disclosed |
| EP-0777658-B1 | SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS | BASF AG (DE) | 1999-12-15 | — | — | EP | disclosed |
| US-5885934-A | HERBICIDES OR FOR THE DESICCATION/DEFOLIATION OF PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | disclosed |
| EP-0777658-A1 | SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005179-A1 | SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-22 | — | — | WO | disclosed |