Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.45 |
| ▸ | KDM6B | O15054 | 2/20 | 0.45 |
| ▸ | KDM5C | P41229 | 2/20 | 0.45 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid Diethyl Ester SCHEMBL27966388 | 0.93 | MGAM (0.55) | CYP1A2MGAMGAASIMGAM2 | |
| SCHEMBL363334 | 0.93 | MGAM (0.55) | CYP1A2MGAMGAASIMGAM2 | |
| SCHEMBL262913 | 0.93 | MGAM (0.55) | CYP1A2MGAMGAASIMGAM2 | |
| Succinic Acid Diethyl Ester SCHEMBL27830938 | 0.93 | MGAM (0.55) | CYP1A2MGAMGAASIMGAM2 | |
| SCHEMBL5014278 | 0.91 | MGAM (0.52) | CYP1A2MGAMGAASIMGAM2 | |
| Methyl Alcohol SCHEMBL2707570 | 0.91 | MGAM (0.52) | CYP1A2MGAMGAASIMGAM2 | |
| Water SCHEMBL1110192 | 0.91 | MGAM (0.52) | CYP1A2MGAMGAASIMGAM2 | |
| SCHEMBL10784546 | 0.91 | MGAM (0.52) | CYP1A2MGAMGAASIMGAM2 | |
| SCHEMBL818402 | 0.91 | MGAM (0.52) | CYP1A2MGAMGAASIMGAM2 | |
| Hydrochloric Acid SCHEMBL1006465 | 0.91 | MGAM (0.52) | CYP1A2MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874464-A | ANTAGONIST OF PROTEIN KINASE C | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-02-23 | — | — | US | disclosed |
| US-5145910-A | Ketocarboxylated polymers | SHELL OIL COMPANY (US) | 1992-09-08 | — | — | US | disclosed |
| US-4208420-A | ANALGESICS, VASOREGULATOR, SYMPATHETIC STIMULANTS | LABORATOIRES JACQUES LOGEAIS (FR) | 1980-06-17 | — | — | US | disclosed |