Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8352321 | 0.88 | HTR2B (0.44) | F10ITGB3ITGA2BHTR2BGPR119 | |
| SCHEMBL8551353 | 0.83 | HTR2B (0.42) | HTR2BGPR119 | |
| SCHEMBL8351626 | 0.83 | ALDH1A1 (0.43) | KMT2AALDH1A1GAARAB9AHTR2B | |
| SCHEMBL8351510 | 0.81 | PTPN11 (0.42) | F10ALDH1A1GAAITGB3PRSS1 | |
| SCHEMBL6180885 | 0.81 | MAPT (0.53) | KMT2AALDH1A1GAAMAPTRAB9A | |
| SCHEMBL8590784 | 0.76 | HRH3 (0.40) | F10ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL8352742 | 0.75 | MAPT (0.46) | F10KMT2AALDH1A1GAAITGB3 | |
| SCHEMBL8355309 | 0.74 | HTR2B (0.47) | F10ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL8350743 | 0.74 | HTR2B (0.43) | F10ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL8350913 | 0.73 | F10 (0.44) | F10KMT2AALDH1A1GAAITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972947-A | ANTICOAGULANT, CARDIOVASCULAR DISORDERS, ANTIINFLAMMATORY AGENTS, OSTEOPOROSIS, ANTITUMOR AGENT | ROCHE DIAGNOSTICS GMBH (DE) | 1999-10-26 | — | — | US | disclosed |