Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.66 |
| ▸ | FAP | Q12884 | 9/20 | 0.66 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.66 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.66 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5204316 | 0.99 | DPP4 (0.64) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL14364704 | 0.85 | DPP4 (0.47) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL14421527 | 0.83 | DPP4 (0.68) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL5206543 | 0.81 | DPP4 (0.52) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL5549926 | 0.78 | DPP4 (0.80) | DPP4FAPDPP7DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5205200 | 0.78 | DPP4 (0.67) | DPP4FAPDPP7DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL3157260 | 0.77 | DPP4 (0.79) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL3791373 | 0.77 | DPP4 (0.61) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL1150129 | 0.77 | DPP4 (0.61) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL3788596 | 0.77 | DPP4 (0.61) | DPP4FAPDPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003002531-A2 | FLUOROPYRROLIDINES AS DIPEPTIDYL PEPTIDASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-01-09 | — | — | WO | disclosed |