Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1402900 | 0.76 | L3MBTL1 (0.59) | L3MBTL1EPHX2HSD11B1HSD17B10ALDH1A1 | |
| SCHEMBL12968364 | 0.74 | L3MBTL1 (0.72) | L3MBTL1EPHX2HSD11B1HSD17B10ALDH1A1 | |
| SCHEMBL13702321 | 0.74 | L3MBTL1 (0.72) | L3MBTL1EPHX2HSD11B1HSD17B10ALDH1A1 | |
| SCHEMBL1016262 | 0.73 | L3MBTL1 (0.65) | L3MBTL1EPHX2HSD11B1HSD17B10ALDH1A1 | |
| SCHEMBL19808153 | 0.72 | L3MBTL1 (0.63) | L3MBTL1EPHX2HSD11B1HSD17B10ALDH1A1 | |
| SCHEMBL25358145 | 0.72 | L3MBTL1 (0.68) | L3MBTL1EPHX2HSD11B1HSD17B10ALDH1A1 | |
| SCHEMBL12344537 | 0.72 | L3MBTL1 (1.00) | L3MBTL1EPHX2HSD11B1HSD17B10ALDH1A1 | |
| SCHEMBL10768733 | 0.71 | EPHX2 (0.57) | L3MBTL1EPHX2HSD11B1HSD17B10 | |
| SCHEMBL10768735 | 0.71 | EPHX2 (0.57) | L3MBTL1EPHX2HSD11B1HSD17B10 | |
| SCHEMBL4229104 | 0.71 | L3MBTL1 (0.61) | L3MBTL1EPHX2HSD11B1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186741-B2 | Neurotensin active 2,3,diaryl-pyrazolidine derivatives | SOLVAY PHARMACEUTICALS B.V. (NL) | 2007-03-06 | — | — | US | disclosed |
| US-7186741-B2 | Neurotensin active 2,3,diaryl-pyrazolidine derivatives | SOLVAY PHARMACEUTICALS B.V. (NL) | 2007-03-06 | — | — | US | disclosed |
| WO-2003078400-A1 | NEUROTENSIN ACTIVE 2,3-DIARYL-PYRAZOLIDINE DERIVATIVES | SOLVAY PHARMACEUTICALS B.V. (NL) | 2003-09-25 | — | — | WO | disclosed |