Flufenoxuron

Flufenoxuron

SCHEMBL8352196

NCCCCN.O=C(NC(=O)c1c(F)cccc1F)Nc1ccc(Oc2ccc(C(F)(F)F)cc2Cl)cc1F

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
USP2 O75604 1/20 0.48
MAPT P10636 1/20 0.48
ALOX15 P16050 1/20 0.48
TLR8 Q9NR97 3/20 0.47
TLR7 Q9NYK1 2/20 0.46
BRAF P15056 9/20 0.44
FFAR1 O14842 2/20 0.43
KDR P35968 2/20 0.42
MAPK14 Q16539 1/20 0.42
TNNI3K Q59H18 1/20 0.42
IL2 P60568 1/20 0.41
MRGPRX4 Q96LA9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flufenoxuron SCHEMBL8407576 0.95 MEN1 (0.52) MEN1KMT2AUSP2MAPTALOX15
Flufenoxuron SCHEMBL29413952 0.95 MEN1 (0.52) MEN1KMT2AUSP2MAPTALOX15
Flufenoxuron SCHEMBL27798 0.95 MEN1 (0.52) MEN1KMT2AUSP2MAPTALOX15
SCHEMBL9325616 0.93 MEN1 (0.51) MEN1KMT2AUSP2MAPTALOX15
Flufenoxuron SCHEMBL28899111 0.92 MEN1 (0.50) MEN1KMT2AUSP2MAPTALOX15
Flufenoxuron SCHEMBL9274900 0.89 TLR8 (0.52) MEN1KMT2AUSP2MAPTALOX15
SCHEMBL13620475 0.89 TLR8 (0.47) MEN1KMT2AUSP2MAPTALOX15
SCHEMBL31499167 0.87 TLR8 (0.51) MEN1KMT2AUSP2MAPTALOX15
SCHEMBL10338942 0.87 BRAF (0.46) MEN1KMT2AUSP2MAPTALOX15
SCHEMBL10339846 0.85 TLR8 (0.49) MEN1KMT2AUSP2MAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5859148-A FRACTURING MOLTEN POLYAMIDE, REACTING FRAGMENT RELEASED WITH ORGANIC COMPOUND HAVING AT LEAST THREE IDENTICAL REACTIVE FUNCTIONAL GROUPS TO FORM STAR BRANCHED POLYMER DSM N.V. (NL) 1999-01-12 US disclosed
US-5788989-A BLOCKED END GROUPS, PROTECTING GROUPS, OCCLUSION OF DRUGS, AGROCHEMICALS, POLYPROPYLAMINE DSM N.V. (NL) 1998-08-04 US disclosed