Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.68 |
| ▸ | HTR2A | P28223 | 2/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8338201 | 0.94 | MAOA (0.72) | MAOAHTR2ACYP2A6SMN1; SMN2TAAR1 | |
| SCHEMBL52482 | 0.89 | MAOA (0.85) | MAOAHTR2ACYP2A6SMN1; SMN2TAAR1 | |
| Benzene SCHEMBL28170833 | 0.89 | MAOA (0.85) | MAOAHTR2ACYP2A6SMN1; SMN2TAAR1 | |
| 4-Phenyl-Butylamine SCHEMBL27597406 | 0.88 | MAOA (0.76) | MAOAHTR2ACYP2A6SMN1; SMN2TAAR1 | |
| SCHEMBL9158637 | 0.87 | MAOA (0.62) | MAOAHTR2ACYP2A6SMN1; SMN2TAAR1 | |
| Bromide SCHEMBL5311946 | 0.86 | MAOA (0.81) | MAOAHTR2ACYP2A6SMN1; SMN2TAAR1 | |
| Iodide SCHEMBL6672340 | 0.86 | MAOA (0.81) | MAOAHTR2ACYP2A6SMN1; SMN2TAAR1 | |
| Hydrochloric Acid SCHEMBL1551608 | 0.86 | MAOA (0.81) | MAOAHTR2ACYP2A6SMN1; SMN2TAAR1 | |
| Water SCHEMBL28661260 | 0.86 | MAOA (0.81) | MAOAHTR2ACYP2A6SMN1; SMN2TAAR1 | |
| Ammonia Solution, Strong SCHEMBL7296242 | 0.86 | MAOA (0.81) | MAOAHTR2ACYP2A6SMN1; SMN2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946549-A1 | COMBINATORIAL PROCESS FOR PREPARING FUSED PYRIMIDINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1999031506-A9 | PARALLEL SOLUTION PHASE SYNTHESIS OF LACTAMS | LILLY CO ELI (US) | 1999-09-16 | — | — | WO | disclosed |
| WO-1999031507-A1 | PEPTIDOMIMETIC TEMPLATE-BASED COMBINATORIAL LIBRARIES | ELI LILLY AND COMPANY (US) | 1999-06-24 | — | — | WO | disclosed |
| WO-1999031506-A1 | PARALLEL SOLUTION PHASE SYNTHESIS OF LACTAMS | ELI LILLY AND COMPANY (US) | 1999-06-24 | — | — | WO | disclosed |
| WO-1998027087-A1 | COMBINATORIAL PROCESS FOR PREPARING FUSED PYRIMIDINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |