Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | LMNA | P02545 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | GAA | P10253 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.66 |
| ▸ | GRM5 | P41594 | 8/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17610429 | 0.87 | GRM5 (0.56) | MAPTLMNAMEN1GAAKMT2A | |
| SCHEMBL5011993 | 0.84 | ADORA1 (0.52) | MAPTLMNAMEN1GAAKMT2A | |
| SCHEMBL5010555 | 0.84 | GFER (0.61) | MAPTLMNAMEN1GAAKMT2A | |
| SCHEMBL17619646 | 0.83 | GRM5 (0.53) | MAPTLMNAMEN1GAAKMT2A | |
| SCHEMBL5008346 | 0.83 | GFER (0.80) | MAPTLMNAMEN1GAAKMT2A | |
| SCHEMBL5008423 | 0.83 | GFER (0.74) | MAPTLMNAMEN1GAAKMT2A | |
| SCHEMBL14600271 | 0.82 | GRM5 (0.49) | MAPTLMNAMEN1GAAKMT2A | |
| SCHEMBL27637162 | 0.81 | MAPT (0.47) | MAPTLMNAMEN1GAAKMT2A | |
| SCHEMBL5010620 | 0.81 | MAPT (0.51) | MAPTLMNAMEN1GAAKMT2A | |
| SCHEMBL14132972 | 0.81 | GRM5 (0.77) | MAPTLMNAMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050651-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-06-17 | — | — | WO | disclosed |