Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | FTO | Q9C0B1 | 10/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14600224 | 0.86 | HPGD (0.51) | GRM5FTOMEN1LMNAGAA | |
| SCHEMBL14600486 | 0.83 | PDE4B (0.43) | FTOMEN1LMNAGAAMAPT | |
| SCHEMBL14600686 | 0.83 | FTO (0.40) | GRM5FTOMEN1LMNAGAA | |
| SCHEMBL8352302 | 0.82 | MAPT (0.66) | GRM5MEN1LMNAGAAMAPT | |
| SCHEMBL14600681 | 0.82 | DHODH (0.44) | FTOMEN1LMNAGAAMAPT | |
| SCHEMBL14600499 | 0.78 | FABP3 (0.45) | MAPTFABP3FABP4 | |
| SCHEMBL5011993 | 0.77 | ADORA1 (0.52) | MEN1LMNAGAAMAPTKMT2A | |
| SCHEMBL4668570 | 0.77 | GFER (0.42) | FTOMEN1LMNAGAAMAPT | |
| Hydrochloric Acid SCHEMBL4669539 | 0.76 | GFER (0.41) | FTOMEN1LMNAGAAMAPT | |
| SCHEMBL14600676 | 0.76 | DHODH (0.46) | FTOFABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |