Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.32 |
| ▸ | TK2 | O00142 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8353147 | 1.00 | PLA2G2C (0.42) | PLA2G2CPLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL8352500 | 1.00 | PLA2G2C (0.42) | PLA2G2CPLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL8347104 | 1.00 | PLA2G2C (0.42) | PLA2G2CPLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL8356122 | 0.94 | PLA2G2C (0.46) | PLA2G2CPLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL8352925 | 0.94 | PLA2G2C (0.46) | PLA2G2CPLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL8353598 | 0.94 | PLA2G2C (0.46) | PLA2G2CPLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL8346912 | 0.94 | PLA2G2C (0.46) | PLA2G2CPLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL8347160 | 0.94 | PLA2G2C (0.46) | PLA2G2CPLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL8352304 | 0.94 | PLA2G2C (0.46) | PLA2G2CPLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL8347107 | 0.89 | PLA2G2A (0.35) | PLA2G2CPLA2G2APLA2G10PLA2G1BPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972982-A | CONTAINING 5-TO 9-MEMBERED HETEROARYL MONO- OR BICYCLIC RING SYSTEM HAVING NO MORE THAN 1 CARBONYL CARBON IN THE RING SYSTEM; VIRICIDES, BACTERICIDES | CLARION PHARMACEUTICALS INC. (US) | 1999-10-26 | — | — | US | disclosed |
| US-5707978-A | ANTITUMOR AGENTS, PSORIASIS, ANTIINFLAMMATORY AGENTS | CLARION PHARMACEUTICALS INC. (US) | 1998-01-13 | — | — | US | disclosed |