Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4172455 | 0.85 | MAOB (0.46) | NR3C1PGRNR3C2ARMAPT | |
| SCHEMBL4172460 | 0.85 | MAOB (0.46) | NR3C1PGRNR3C2ARMAPT | |
| SCHEMBL4155418 | 0.85 | AR (0.58) | NR3C1PGRNR3C2ARMAPT | |
| SCHEMBL13802885 | 0.85 | MIF (0.54) | NR3C1PGRNR3C2ARMAPT | |
| SCHEMBL8350579 | 0.85 | NR3C1 (0.48) | NR3C1PGRNR3C2ARMAPT | |
| SCHEMBL13802908 | 0.85 | NR3C1 (0.43) | NR3C1PGRNR3C2ARMAPT | |
| SCHEMBL14092367 | 0.85 | NR3C1 (0.43) | NR3C1PGRNR3C2ARMAPT | |
| SCHEMBL14092364 | 0.79 | NR3C1 (0.77) | NR3C1PGRNR3C2ARMAPT | |
| SCHEMBL13802915 | 0.79 | NR3C1 (0.77) | NR3C1PGRNR3C2ARMAPT | |
| SCHEMBL13802918 | 0.79 | NR3C1 (0.77) | NR3C1PGRNR3C2ARMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004052847-A2 | TRICYCLIC STEROID HORMONE NUCLEAR RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-06-24 | — | — | WO | disclosed |