Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354141 | 0.91 | ALDH1A1 (0.58) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL8351069 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL8350094 | 0.78 | POLB (0.59) | ALDH1A1KMT2AMEN1LMNATSHR | |
| SCHEMBL8350476 | 0.75 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1LMNATSHR | |
| SCHEMBL8350643 | 0.74 | MAPT (0.50) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL11160437 | 0.74 | ALDH1A1 (0.60) | ALDH1A1KDM4EKMT2AMEN1CYP2C9 | |
| SCHEMBL8353674 | 0.73 | MAPT (0.61) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL8350533 | 0.73 | POLB (0.57) | ALDH1A1KMT2AMEN1LMNATSHR | |
| SCHEMBL8350048 | 0.72 | SMN1; SMN2 (0.59) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL8353740 | 0.72 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999031096-A1 | PIPERAZINE DERIVATIVES USEFUL AS HYPOGLYCEMIC AGENTS | SHAMAN PHARMACEUTICALS, INC. (US) | 1999-06-24 | — | — | WO | claimed |