Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 19/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 13/20 | 0.41 |
| ▸ | ITGB6 | P18564 | 6/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | ITGB8 | P26012 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21715687 | 0.94 | ITGAV (0.39) | ITGAVITGB3ITGB6CXCR4ITGB8 | |
| SCHEMBL21715684 | 0.87 | ITGAV (0.40) | ITGAVITGB3ITGB6CXCR4ITGB8 | |
| SCHEMBL279379 | 0.80 | CXCR4 (0.42) | ITGAVITGB3ITGB6CXCR4ITGB8 | |
| SCHEMBL325378 | 0.76 | CXCR4 (0.39) | ITGAVITGB3ITGB6CXCR4ITGB8 | |
| SCHEMBL19544248 | 0.75 | CXCR4 (0.39) | ITGAVITGB3ITGB6CXCR4ITGB8 | |
| SCHEMBL7435472 | 0.75 | ITGAV (0.54) | ITGAVITGB3ITGB6 | |
| SCHEMBL7797597 | 0.74 | ITGAV (0.51) | ITGAVITGB3ITGB6CXCR4 | |
| SCHEMBL12895016 | 0.73 | ITGAV (0.47) | ITGAVITGB3ITGB6CXCR4 | |
| SCHEMBL5373708 | 0.73 | ITGAV (0.39) | ITGAVITGB3ITGB6CXCR4ITGB8 | |
| SCHEMBL4530325 | 0.72 | ITGAV (0.43) | ITGAVITGB3ITGB6CXCR4ITGB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070914-A1 | New antagonist derivatives of the vitronectin receiver, method for preparing same, application of same as medicine and pharmaceutical compositions containing them | Galapagos SAS (FR) | 2009-06-17 | — | — | EP | disclosed |
| WO-2004048375-A1 | NOVEL VITRONECTIN RECEPTOR ANTAGONIST DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | PROSKELIA SAS (FR) | 2004-06-10 | — | — | WO | disclosed |