Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 13/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17713567 | 0.85 | TLR8 (0.63) | TLR8 | |
| SCHEMBL28743898 | 0.84 | TLR8 (0.61) | TLR8ALDH1A1GLAHPGDKDM4E | |
| SCHEMBL287399 | 0.84 | TLR8 (0.61) | TLR8ALDH1A1GLAHPGDKDM4E | |
| SCHEMBL27524779 | 0.83 | TLR8 (0.62) | TLR8ALDH1A1GLAHPGDKDM4E | |
| SCHEMBL11829305 | 0.78 | TLR8 (0.39) | TLR8ALDH1A1GLAHPGDKDM4E | |
| Acridine SCHEMBL27894463 | 0.78 | MAPT (0.68) | TLR8ALDH1A1GLAHPGDKDM4E | |
| SCHEMBL28521043 | 0.77 | TLR8 (0.56) | TLR8 | |
| SCHEMBL31463622 | 0.77 | PIK3CD (0.43) | TLR8ALDH1A1GLAHPGDKDM4E | |
| SCHEMBL3390064 | 0.77 | PIK3CD (0.43) | TLR8ALDH1A1GLAHPGDKDM4E | |
| SCHEMBL18583409 | 0.75 | ALDH1A1 (0.47) | TLR8ALDH1A1GLAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021870-A1 | ERYTHROMYCIN A 11, 12-CARBAMATE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-06 | — | — | WO | disclosed |