Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.50 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8356569 | 0.90 | F10 (0.64) | F10SMN1; SMN2TDP1KCNH2KLKB1 | |
| SCHEMBL8353943 | 0.89 | F10 (0.51) | F10SMN1; SMN2TDP1ALDH1A1TSHR | |
| SCHEMBL4856966 | 0.86 | F10 (0.66) | F10KCNH2KLKB1 | |
| SCHEMBL8355348 | 0.85 | F10 (0.65) | F10SMN1; SMN2KCNH2KLKB1ALDH1A1 | |
| SCHEMBL4856391 | 0.83 | F10 (0.63) | F10KCNH2KLKB1ALDH1A1TSHR | |
| SCHEMBL3156608 | 0.83 | F10 (0.56) | F10SMN1; SMN2TDP1ALDH1A1TSHR | |
| SCHEMBL4858193 | 0.83 | F10 (0.64) | F10SMN1; SMN2KCNH2KLKB1ALDH1A1 | |
| SCHEMBL5388278 | 0.81 | F10 (0.74) | F10KCNH2KLKB1 | |
| SCHEMBL4857507 | 0.81 | F10 (0.66) | F10SMN1; SMN2TDP1KCNH2KLKB1 | |
| SCHEMBL4852753 | 0.81 | F10 (0.61) | F10KCNH2KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003050088-A1 | SUBSTITUTED HETEROCYCLIC CARBOXAMIDES WITH ANTITHROMBOTIC ACTIVITY | ELI LILLY AND COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |