Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8353486 | 0.91 | F10 (0.66) | F10POLBALDH1A1RAB9ANPC1 | |
| SCHEMBL13313049 | 0.86 | F10 (0.67) | F10POLBKCNH2KLKB1 | |
| SCHEMBL8354573 | 0.85 | F10 (0.64) | F10ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL4856406 | 0.83 | F10 (0.64) | F10POLBALDH1A1RAB9ANPC1 | |
| SCHEMBL3160357 | 0.83 | POLB (0.67) | F10POLBALDH1A1RAB9ANPC1 | |
| SCHEMBL4854339 | 0.83 | F10 (0.71) | F10ALDH1A1KCNH2KLKB1 | |
| SCHEMBL4857992 | 0.83 | F10 (0.63) | F10POLBALDH1A1RAB9ANPC1 | |
| SCHEMBL5383293 | 0.83 | F10 (0.74) | F10KDM4EKCNH2KLKB1 | |
| SCHEMBL4858193 | 0.83 | F10 (0.64) | F10POLBALDH1A1RAB9ANPC1 | |
| SCHEMBL13313056 | 0.81 | F10 (0.62) | F10KCNH2KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003050088-A1 | SUBSTITUTED HETEROCYCLIC CARBOXAMIDES WITH ANTITHROMBOTIC ACTIVITY | ELI LILLY AND COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |