Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.71 |
| ▸ | FAP | Q12884 | 3/20 | 0.50 |
| ▸ | POU2F2 | P09086 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | POU2F1 | P14859 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.50 |
| ▸ | GHSR | Q92847 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354649 | 0.93 | DPP4 (0.81) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL5842872 | 0.91 | DPP4 (0.88) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL5842865 | 0.91 | DPP4 (0.88) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL8354330 | 0.86 | DPP4 (0.69) | DPP4CHRM1CYP3A4 | |
| SCHEMBL12229295 | 0.86 | DPP4 (0.66) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL5842422 | 0.83 | DPP4 (1.00) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL5842437 | 0.83 | DPP4 (1.00) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL2949895 | 0.80 | DPP4 (0.81) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL8283962 | 0.80 | DPP4 (0.63) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL8349851 | 0.79 | DPP4 (0.62) | DPP4CHRM1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050658-A1 | NOVEL SUBSTITUTED IMIDAZO-PYRIDINONES AND IMIDAZO-PYRIDAZEIONES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-06-17 | — | — | WO | disclosed |