Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4429857 | 0.89 | MAPT (0.55) | GPR119SMN1; SMN2KMT2AMEN1NPSR1 | |
| SCHEMBL8349369 | 0.88 | GPR119 (0.50) | GPR119SMN1; SMN2KMT2AMEN1USP2 | |
| SCHEMBL8354830 | 0.88 | GAA (0.55) | GPR119GAAALOX12SMN1; SMN2KMT2A | |
| SCHEMBL8354642 | 0.85 | GPR119 (0.62) | GPR119SMN1; SMN2KMT2AMEN1USP2 | |
| SCHEMBL2959519 | 0.82 | GPR119 (0.74) | GPR119KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8348627 | 0.81 | GPR119 (0.62) | GPR119SMN1; SMN2KMT2AMEN1USP2 | |
| SCHEMBL8352835 | 0.80 | GAA (0.51) | GPR119GAAALOX12SMN1; SMN2KMT2A | |
| SCHEMBL21876731 | 0.80 | GPR119 (0.59) | GPR119KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8352974 | 0.80 | GPR119 (0.59) | GPR119KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL30952688 | 0.79 | MAPT (0.55) | GPR119SMN1; SMN2KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999020606-A2 | PIPERIDINES AND PIPERAZINES AS PLATELET AGGREGATION INHIBITORS | J. URIACH & CIA. S.A. (ES) | 1999-04-29 | — | — | WO | disclosed |