Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Methylpiperidine SCHEMBL11353667 | 0.78 | GAA (0.56) | GAAKDM4EALDH1A1PARP1POLB | |
| SCHEMBL29381201 | 0.78 | KDM4E (0.68) | GAAKDM4EALDH1A1PARP1MEN1 | |
| SCHEMBL43084 | 0.78 | KDM4E (0.68) | GAAKDM4EALDH1A1PARP1MEN1 | |
| SCHEMBL4860337 | 0.77 | GAA (0.50) | GAAKDM2BKDM4EALDH1A1POLB | |
| SCHEMBL14837757 | 0.77 | KDM4E (0.66) | GAAKDM4EALDH1A1PARP1MEN1 | |
| Hydrochloric Acid SCHEMBL3149083 | 0.77 | KDM4E (0.66) | GAAKDM4EALDH1A1PARP1MEN1 | |
| Hydrochloric Acid SCHEMBL30753709 | 0.77 | KDM4E (0.66) | GAAKDM4EALDH1A1PARP1MEN1 | |
| SCHEMBL9011545 | 0.77 | KDM4E (0.66) | GAAKDM4EALDH1A1PARP1MEN1 | |
| SCHEMBL18859029 | 0.77 | KDM4E (0.66) | GAAKDM4EALDH1A1PARP1MEN1 | |
| SCHEMBL18859030 | 0.77 | KDM4E (0.66) | GAAKDM4EALDH1A1PARP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060773-C | Naphthamide derivs, of 3-beta-amino azabicyclo octane or nonane as neuroleptic agents | PF MEDICAMENT (FR) | 2001-01-17 | — | — | CN | disclosed |
| US-5958945-A | PSYCHOLOGICAL DISORDERS | PIERRE FABRE MEDICAMENT (FR) | 1999-09-28 | — | — | US | disclosed |
| CN-1199399-A | Naphthamide derivs, of 3-beta-amino azabicyclo octane or nonane as neuroleptic agents | PF MEDICAMENT (FR) | 1998-11-18 | — | — | CN | disclosed |