Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | PPARA | Q07869 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.53 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319605 | 0.93 | LMNA (0.83) | LMNASMN1; SMN2POLBPPARAL3MBTL1 | |
| SCHEMBL8151680 | 0.91 | LMNA (0.62) | LMNAPPARAALDH1A1MAPTLTB4R | |
| SCHEMBL8148742 | 0.91 | LMNA (0.62) | LMNAPPARAALDH1A1MAPTLTB4R | |
| SCHEMBL8161670 | 0.91 | LMNA (0.62) | LMNAPPARAALDH1A1MAPTLTB4R | |
| SCHEMBL8162525 | 0.91 | LMNA (0.62) | LMNAPPARAALDH1A1MAPTLTB4R | |
| SCHEMBL8163174 | 0.91 | LMNA (0.62) | LMNAPPARAALDH1A1MAPTLTB4R | |
| SCHEMBL8158709 | 0.91 | LMNA (0.62) | LMNAPPARAALDH1A1MAPTLTB4R | |
| SCHEMBL8162827 | 0.90 | LMNA (0.61) | LMNAPPARAALDH1A1MAPTLTB4R | |
| SCHEMBL8148979 | 0.90 | LMNA (0.61) | LMNAPPARAALDH1A1MAPTLTB4R | |
| SCHEMBL8164009 | 0.90 | LMNA (0.61) | LMNAPPARAALDH1A1MAPTLTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999029640-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR | EISAI CO., LTD. (JP) | 1999-06-17 | — | — | WO | claimed |
| WO-1999029640-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR | EISAI CO., LTD. (JP) | 1999-06-17 | — | — | WO | disclosed |