Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8352204 | 0.93 | SYK (0.40) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL8550242 | 0.90 | HTR2B (0.38) | HTR2BHRH4HRH3JAK2JAK1 | |
| SCHEMBL8349896 | 0.88 | SYK (0.43) | F10ITGB3ITGA2BHTR2BF2 | |
| SCHEMBL8352865 | 0.88 | ALK (0.44) | HTR2BSYKJAK2JAK1TYK2 | |
| SCHEMBL8350743 | 0.86 | HTR2B (0.43) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL8351623 | 0.86 | OGA (0.44) | HTR2BSYKHRH4HRH3 | |
| SCHEMBL8550238 | 0.84 | HTR2B (0.40) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL8352433 | 0.82 | HTR2B (0.42) | F10ITGB3ITGA2BHTR2BF2 | |
| SCHEMBL8352321 | 0.81 | HTR2B (0.44) | F10ITGB3ITGA2BHTR2BF2 | |
| SCHEMBL8551028 | 0.78 | HTR2B (0.41) | HTR2BSYKJAK2JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972947-A | ANTICOAGULANT, CARDIOVASCULAR DISORDERS, ANTIINFLAMMATORY AGENTS, OSTEOPOROSIS, ANTITUMOR AGENT | ROCHE DIAGNOSTICS GMBH (DE) | 1999-10-26 | — | — | US | disclosed |