Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 8/20 | 0.35 |
| ▸ | JAK1 | P23458 | 8/20 | 0.35 |
| ▸ | TYK2 | P29597 | 8/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 2/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | BPTF | Q12830 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549444 | 0.90 | OGA (0.45) | HTR2BOGAALKCXCR4IGF1R | |
| SCHEMBL8349896 | 0.89 | SYK (0.43) | HTR2BJAK2JAK1TYK2ALK | |
| SCHEMBL8550242 | 0.89 | HTR2B (0.38) | HTR2BOGAJAK2JAK1TYK2 | |
| SCHEMBL8352865 | 0.84 | ALK (0.44) | HTR2BJAK2JAK1TYK2ALK | |
| SCHEMBL8551353 | 0.83 | HTR2B (0.42) | HTR2BPARP1ADRB3 | |
| SCHEMBL8593632 | 0.79 | HTR2B (0.45) | HTR2BADRB3 | |
| SCHEMBL8552786 | 0.79 | HTR2B (0.45) | HTR2BADRB3 | |
| SCHEMBL8351623 | 0.79 | OGA (0.44) | HTR2BOGAALKCXCR4SYK | |
| SCHEMBL8550693 | 0.79 | HTR2B (0.43) | HTR2BADRB3 | |
| SCHEMBL8355453 | 0.78 | F10 (0.39) | HTR2BJAK2JAK1TYK2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839147-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997003072-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-30 | — | — | WO | disclosed |