Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3184176 | 0.81 | ESR2 (0.47) | ESR2NR1H2MEN1KMT2AMAPK1 | |
| SCHEMBL27621228 | 0.81 | ESR2 (0.46) | ESR2NR1H2MEN1KMT2APTPN2 | |
| SCHEMBL27621240 | 0.81 | MEN1 (0.46) | ESR2NR1H2MEN1KMT2AMAPK1 | |
| SCHEMBL3194232 | 0.80 | SLC6A3 (0.57) | ESR2NR1H2SLC6A3 | |
| SCHEMBL3986657 | 0.80 | ESR2 (0.45) | ESR2NR1H2MEN1KMT2AMAPK1 | |
| SCHEMBL3195957 | 0.80 | NAMPT (0.56) | ESR2MEN1KMT2ANAMPT | |
| SCHEMBL3210586 | 0.79 | ESR2 (0.48) | ESR2NR1H2SLC6A3 | |
| SCHEMBL27621215 | 0.78 | STS (0.52) | ESR2NR1H2MEN1KMT2AMKNK1 | |
| SCHEMBL4756289 | 0.78 | SLC6A3 (0.53) | ESR2NR1H2MEN1KMT2AMAPK1 | |
| SCHEMBL3197591 | 0.78 | SLC6A3 (0.55) | ESR2NR1H2MAPK1SLC6A3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861416-A | TREATMENT OF ASTHMA OR COUGH | MERRELL PHARMACEUTICALS INC. (US) | 1999-01-19 | — | — | US | disclosed |
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |