Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNG2 | P59768 | 3/20 | 0.73 |
| ▸ | GNB1 | P62873 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | MMP1 | P03956 | 1/20 | 0.73 |
| ▸ | MMP9 | P14780 | 1/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.73 |
| ▸ | BLM | P54132 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13320819 | 0.99 | GNG2 (0.71) | GNG2GNB1MEN1MMP1MMP9 | |
| SCHEMBL8356376 | 0.99 | GNG2 (0.71) | GNG2GNB1MEN1MMP1MMP9 | |
| SCHEMBL13320815 | 0.97 | GNG2 (0.73) | GNG2GNB1MEN1MMP1MMP9 | |
| SCHEMBL8355892 | 0.94 | GNG2 (0.65) | GNG2GNB1MEN1MMP1MMP9 | |
| SCHEMBL8358129 | 0.94 | GNG2 (0.65) | GNG2GNB1MEN1MMP1MMP9 | |
| SCHEMBL8358236 | 0.92 | GNG2 (0.73) | GNG2GNB1MEN1MMP1MMP9 | |
| SCHEMBL3238446 | 0.91 | GNG2 (0.71) | GNG2GNB1MEN1MMP1MMP9 | |
| SCHEMBL8352418 | 0.91 | GNG2 (0.79) | GNG2GNB1MEN1MMP1MMP9 | |
| Aminoquinuride SCHEMBL29852258 | 0.85 | GNG2 (1.00) | GNG2GNB1MEN1MMP1MMP9 | |
| SCHEMBL8359605 | 0.85 | GNG2 (0.83) | GNG2GNB1MEN1MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998027815-A1 | SUBSTITUTED AMINOQUINOLINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 1998-07-02 | — | — | WO | claimed |
| US-5919776-A | ANTIINFLAMMATORY AGENT; AUTOIMMUNE DISEASE | MERCK & CO., INC. (US) | 1999-07-06 | — | — | US | disclosed |
| WO-1998027815-A1 | SUBSTITUTED AMINOQUINOLINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 1998-07-02 | — | — | WO | disclosed |