SCHEMBL8356100

SCHEMBL8356100

CC(OS(=O)(=O)O)S(=O)(=O)c1ccccc1N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.46
CA9 Q16790 4/20 0.44
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
CA12 O43570 2/20 0.44
CA4 P22748 2/20 0.44
CA5A P35218 2/20 0.44
CYP2C9 P11712 1/20 0.44
CA6 P23280 1/20 0.44
CA7 P43166 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
HTR6 P50406 1/20 0.41
KYNU Q16719 2/20 0.40
TTR P02766 1/20 0.39
ALDH1A1 P00352 1/20 0.33
CFTR P13569 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7622315 0.84 TTR (0.38) GAACA9CA1CA2CA12
SCHEMBL1357746 0.77 GAA (0.50) GAACA9CA1CA2CA12
SCHEMBL11207535 0.77 GAA (0.54) GAACA9CA1CA2CA12
SCHEMBL14692114 0.76 GAA (0.42) GAACA9CA1CA2CA12
SCHEMBL1015219 0.76 GAA (0.58) GAACA9CA1CA2CA12
SCHEMBL7098293 0.75 SMN1; SMN2 (0.45) GAACA9CA1CA2CA12
SCHEMBL5047408 0.75 CTDSP1 (0.39) GAACA9CA1CA2CA12
Isopropylamine SCHEMBL28821636 0.73 GAA (0.54) GAACA9CA1CA2CA12
SCHEMBL1819324 0.72 TSHR (0.48) GAACA9CA1CA2CA12
SCHEMBL10079051 0.72 PKM (0.55) GAACA1CA2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5922865-A USING AN ANIONIC DYE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-07-13 US disclosed
US-5792222-A ANIONIC ACID SUBSTITUTED-TRIAZINE DYE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-08-11 US disclosed
US-4731441-A Water-soluble azo compounds containing, as fiber-reactive groups, a (nitrophenylamino-phenylamino)-chloro-triazinylamino group and groups of the vinylsulfone series, suitable as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1988-03-15 US disclosed
EP-0092909-A2 Process for producing aminophenyl-beta-hydroxyethylsulfone SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-11-02 EP disclosed