SCHEMBL8356240

SCHEMBL8356240

C=C(C)C(=O)OCCN(C(=O)CC(C)=O)C(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.45
TSHR P16473 3/20 0.40
ALDH1A1 P00352 2/20 0.34
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25486897 0.84 TSHR (0.49) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL21943129 0.83 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL5843413 0.82 THRB (0.44) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL17756350 0.81 THRB (0.41) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL4981371 0.81 THRB (0.43) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL17813797 0.81 THRB (0.43) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL9245482 0.80 THRB (0.47) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL17752919 0.80 THRB (0.40) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL17758703 0.79 THRB (0.42) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL17522089 0.78 THRB (0.41) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5888719-A CONTINING A POLYMER; DARK DECAY STABILITY AGFA-GEVAERT AG (DE) 1999-03-30 US disclosed
EP-0666498-A2 Silver halide photographic material Agfa-Gevaert AG (DE) 1995-08-09 EP disclosed
US-4512969-A Compositions containing hydrophobic addenda uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1985-04-23 US disclosed
EP-0077064-B1 PHOTOGRAPHIC ELEMENT COMPRISING A LAYER CONTAINING A CROSS-LINKED POLYMER EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-03-27 EP disclosed
US-4420555-A Photographic materials containing yellow filter dyes EASTMAN KODAK COMPANY (US) 1983-12-13 US disclosed
EP-0077064-A1 Photographic element comprising a layer containing a cross-linked polymer EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-04-20 EP disclosed
US-4358524-A Polymeric vehicle for metallizable dye image-receiving layer EASTMAN KODAK COMPANY (US) 1982-11-09 US disclosed
US-4304769-A PESTICIDES EASTMAN KODAK COMPANY (US) 1981-12-08 US disclosed
US-4247627-A Photographic elements having hydrophilic colloid layers containing hydrophobic ultraviolet absorbers uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1981-01-27 US disclosed
US-4214047-A Photographic elements having hydrophilic colloid layers containing hydrophobic addenda uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1980-07-22 US disclosed
US-4203716-A Photographic elements having hydrophilic colloid layers containing hydrophobic addenda uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1980-05-20 US disclosed
US-4199363-A Processes for achieving uniform, efficient distribution of hydrophobic materials through hydrophilic colloid layers and loaded latex compositions EASTMAN KODAK COMPANY (US) 1980-04-22 US disclosed
US-4133687-A Photographic elements having hydrophilic colloid layers containing compounds having activator precursors and hydrophobic developing agents uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1979-01-09 US disclosed