SCHEMBL8356359

SCHEMBL8356359

CC(C)(Cc1ccccc1)CC(C(=O)O)C(CC(C)(C)Cc1ccccc1)(C(=O)O)S(=O)(=O)O.[NaH]

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.35
HIF1A Q16665 1/20 0.35
CYP3A4 P08684 2/20 0.33
CYP1A2 P05177 1/20 0.33
RECQL P46063 1/20 0.33
PTPN2 P17706 1/20 0.33
PTPN1 P18031 1/20 0.33
PTPRA P18433 1/20 0.33
PTPRB P23467 1/20 0.33
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33
MAPK1 P28482 1/20 0.33
TRPA1 O75762 1/20 0.33
ALDH1A1 P00352 2/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
MMP1 P03956 4/20 0.32
MMP13 P45452 4/20 0.32
MMP9 P14780 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8356358 0.81 ALDH1A1 (0.33) SMN1; SMN2HIF1ACYP3A4CYP1A2RECQL
SCHEMBL18342943 0.74 CYP1A2 (0.43) SMN1; SMN2HIF1ACYP1A2MMP9CPA1
SCHEMBL3663210 0.70
SCHEMBL8410436 0.69 TSHR (0.39) SMN1; SMN2CYP3A4CYP1A2MAPK1ALDH1A1
SCHEMBL1835148 0.68 ALPI (0.55) SMN1; SMN2HIF1ACYP3A4CYP1A2RECQL
SCHEMBL1835145 0.68 ALPI (0.55) SMN1; SMN2HIF1ACYP3A4CYP1A2RECQL
SCHEMBL8408623 0.67 TSHR (0.40) SMN1; SMN2CYP3A4CYP1A2MAPK1ALDH1A1
SCHEMBL34465095 0.67 SMN1; SMN2 (0.39) SMN1; SMN2HIF1ACYP3A4CYP1A2PTPN2
SCHEMBL8410582 0.67 SRC (0.40) MAPK1TRPA1ALDH1A1MAPTTAAR1
SCHEMBL6726914 0.65 SLC6A2 (0.48) SMN1; SMN2HIF1ACYP3A4CYP1A2RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5998120-A Process for making a direct dispersion of a photographically useful material EASTMAN KODAK COMPANY (US) 1999-12-07 US disclosed
US-5952521-A A DI-PHENYLALKYL SULPHOSUCCINATE DISPERSANT FOR IMPROVING PHOTOGRAPHIC PERFORMANCE WITH DISPERSIONS OF A PHOTOGRAPHIC COUPLER IN A HYDROPHILIC COLLOID EASTMAN KODAK COMPANY (US) 1999-09-14 US disclosed
US-5763150-A DISPERSING AIDS; PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1998-06-09 US disclosed