Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 18/20 | 0.52 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.52 |
| ▸ | DRD5 | P21918 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8244135 | 0.82 | GALR3 (0.76) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL8356127 | 0.82 | GALR3 (0.46) | GALR3HTR4NR1H3 | |
| SCHEMBL5907038 | 0.73 | GALR3 (0.77) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL915969 | 0.72 | GALR3 (0.83) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL915968 | 0.72 | GALR3 (0.83) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL8410768 | 0.72 | KMT2A (0.50) | GALR3HTR4NR1H3 | |
| SCHEMBL5807393 | 0.71 | GALR3 (0.71) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL8358674 | 0.71 | NR1H3 (0.44) | GALR3HTR4NR1H3 | |
| SCHEMBL5356928 | 0.71 | GALR3 (0.81) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL5356925 | 0.71 | GALR3 (0.81) | GALR3HTR4DRD5ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014854-A1 | 3-IMINO-2-INDOLONES FOR THE TREATMENT OF DEPRESSION AND/OR ANXIETY | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2004-02-19 | — | — | WO | disclosed |