Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | DNTT | P04053 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10137633 | 0.80 | KMT2A (0.58) | KMT2ABACE1TSHRNPSR1HTT | |
| SCHEMBL18576562 | 0.78 | KMT2A (0.57) | KMT2ABACE1TSHRNPSR1HTT | |
| SCHEMBL30320818 | 0.75 | KMT2A (0.53) | KMT2ABACE1TSHRHTTALDH1A1 | |
| SCHEMBL24829914 | 0.70 | TSHR (0.45) | TSHRNPSR1 | |
| SCHEMBL903366 | 0.69 | ALDH1A1 (0.40) | KMT2ATSHRHTTALDH1A1CYP1A2 | |
| SCHEMBL1977876 | 0.69 | ALDH1A1 (0.40) | KMT2ATSHRHTTALDH1A1CYP1A2 | |
| SCHEMBL15123414 | 0.68 | KMT2A (0.46) | KMT2ABACE1HTT | |
| SCHEMBL15123413 | 0.68 | KMT2A (0.46) | KMT2ABACE1HTT | |
| SCHEMBL9664010 | 0.67 | KMT2A (0.72) | KMT2ABACE1TSHRHTTCYP1A2 | |
| SCHEMBL9326232 | 0.66 | KMT2A (0.61) | KMT2ABACE1NPSR1HTTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003062265-A2 | NOVEL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2003-07-31 | — | — | WO | disclosed |