Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.47 |
| ▸ | KDM1A | O60341 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30723279 | 1.00 | S1PR5 (0.48) | S1PR5MRGPRX4KDM1AMAPTMAPK1 | |
| SCHEMBL20807100 | 0.84 | MAPT (0.48) | MAPTMAPK1TDP1L3MBTL1NPC1 | |
| SCHEMBL30719648 | 0.82 | MRGPRX4 (0.53) | S1PR5MRGPRX4KDM1AMAPTMAPK1 | |
| SCHEMBL412514 | 0.82 | MRGPRX4 (0.53) | S1PR5MRGPRX4KDM1AMAPTMAPK1 | |
| SCHEMBL1128800 | 0.81 | S1PR5 (0.52) | S1PR5MRGPRX4KDM1AERN1NPC1 | |
| SCHEMBL10176688 | 0.81 | FFAR4 (0.57) | MRGPRX4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL371725 | 0.79 | MAOB (0.53) | S1PR5MRGPRX4KDM1AMAPTL3MBTL1 | |
| SCHEMBL12260990 | 0.79 | NPC1 (0.56) | MRGPRX4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL224277 | 0.79 | KDM1A (0.55) | S1PR5KDM1APTGER1 | |
| SCHEMBL30739242 | 0.79 | KDM1A (0.55) | S1PR5KDM1APTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106242973-A | Polymerizable compounds and their use in liquid crystal displays | 默克专利股份有限公司 | 2016-12-21 | — | — | CN | disclosed |
| EP-2352374-B1 | NOVEL CYCLIC BENZIMIDAZOLE DERIVATIVES USEFUL ANTI-DIABETIC AGENTS | MERCK SHARP & DOHME (US) | 2014-09-24 | — | — | EP | disclosed |
| WO-2003053915-A2 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2003-07-03 | — | — | WO | disclosed |