Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3687012 | 0.81 | MGAM (0.36) | SMN1; SMN2GAAMGAMSIMGAM2 | |
| SCHEMBL3684680 | 0.81 | CA1 (0.44) | SMN1; SMN2GAAMGAMSIMGAM2 | |
| SCHEMBL188112 | 0.80 | SMN1; SMN2 (0.38) | SMN1; SMN2GAAMGAMSIMGAM2 | |
| SCHEMBL7977852 | 0.80 | SMN1; SMN2 (0.38) | SMN1; SMN2GAAMGAMSIMGAM2 | |
| SCHEMBL24072865 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2GAACA1CA2CA14 | |
| SCHEMBL1557617 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2GAACA1CA2CA14 | |
| SCHEMBL9517409 | 0.78 | NAALAD2 (0.42) | EPHX1LMNA | |
| SCHEMBL15915435 | 0.77 | ALOX15 (0.36) | EPHX1LMNA | |
| SCHEMBL28760883 | 0.76 | EPHX1 (0.36) | SMN1; SMN2EPHX1LMNATSHR | |
| SCHEMBL765786 | 0.75 | CA14 (0.44) | SMN1; SMN2CA14ALDH1A1CA12BIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048120-A2 | 2-ARYL PYRROLOGPYRIMIDINES FOR A1 AND A3 RECEPTORS | OSI PHARMACEUTICALS, INC. (US) | 2003-06-12 | — | — | WO | disclosed |