SCHEMBL8357680

SCHEMBL8357680

C=C(C(=O)O)C(C)C=Cc1ccccc1.C=CS(N)(=O)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.40
CYP1A2 P05177 2/20 0.40
AHR P35869 1/20 0.39
CYP2C19 P33261 1/20 0.39
LMNA P02545 3/20 0.38
MAPT P10636 3/20 0.38
GAA P10253 2/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP3A4 P08684 1/20 0.37
TDP1 Q9NUW8 3/20 0.37
GLA P06280 1/20 0.37
HDAC3 O15379 2/20 0.36
HDAC4 P56524 2/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC7 Q8WUI4 2/20 0.36
HDAC2 Q92769 2/20 0.36
HDAC10 Q969S8 2/20 0.36
HDAC11 Q96DB2 2/20 0.36
HDAC8 Q9BY41 2/20 0.36
HDAC6 Q9UBN7 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL179701 0.88 CYP1A2 (0.49) HTTCYP1A2LMNAMAPTALDH1A1
Butadiene SCHEMBL14976845 0.86 CYP1A2 (0.45) HTTCYP1A2CYP2C19LMNAMAPT
Methacrylic Acid SCHEMBL4915338 0.83 TDP1 (0.46) HTTCYP1A2LMNAMAPTALDH1A1
Acrylonitrile SCHEMBL17443016 0.81 CYP1A2 (0.41) HTTCYP1A2CYP2C19LMNAMAPT
SCHEMBL11800512 0.75 MEN1 (0.39) CYP1A2LMNAMAPTALDH1A1TDP1
SCHEMBL4250754 0.73 CYP1A2 (0.50) CYP1A2LMNAMAPTGAAALDH1A1
SCHEMBL9113413 0.73 CYP1A2 (0.50) HTTCYP1A2CYP2C19LMNAMAPT
SCHEMBL21853677 0.73 CYP1A2 (0.50) HTTCYP1A2CYP2C19LMNAMAPT
SCHEMBL11753579 0.72 CYP1A2 (0.58) HTTCYP1A2AHRCYP2C19LMNA
SCHEMBL11753570 0.72 CYP1A2 (0.58) HTTCYP1A2AHRCYP2C19LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5882841-A ULTRAHIGH CONTRAST, STORAGE STABILITY, UNIFORMITY, POLYMER PARTICLES CONTAINING A HYDRAZINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1999-03-16 US disclosed
EP-0317983-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1994-06-01 EP disclosed
US-5200304-A Having uniform cyan dye density; capable of being processed at high speeds, storage stable FUJI PHOTO FILM CO., LTD. (JP) 1993-04-06 US disclosed
US-5100771-A SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL WITH WATER INSOLUBLE ORGANIC SOLVENT SOLUBLE POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1992-03-31 US disclosed
US-5047314-A Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-09-10 US disclosed
EP-0435179-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-07-03 EP disclosed
EP-0317983-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-31 EP disclosed