Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.55 |
| ▸ | GAA | P10253 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811530 | 0.83 | MAPT (0.65) | MAPTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL18435400 | 0.80 | CA12 (0.64) | KDM4E | |
| SCHEMBL7106742 | 0.80 | CA12 (0.64) | KDM4E | |
| SCHEMBL8357883 | 0.79 | CA2 (0.49) | MAPTRAB9ANPC1KDM4EMEN1 | |
| SCHEMBL14354212 | 0.78 | MAPT (0.63) | MAPTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL14354091 | 0.78 | MAPT (0.63) | MAPTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL14354213 | 0.78 | MAPT (0.63) | MAPTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL14354131 | 0.78 | MAPT (0.63) | MAPTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL14354015 | 0.78 | MAPT (0.63) | MAPTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL14354014 | 0.78 | MAPT (0.63) | MAPTRAB9ANPC1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998645-A | LAUNDERING DETERGENTS; CLEANING COMPOUNDS | CLARIANT GMBH (DE) | 1999-12-07 | — | — | US | disclosed |