Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8350635 | 0.84 | MAPT (0.58) | ALDH1A1MAPTKDM4ELMNAPOLB | |
| SCHEMBL8352629 | 0.83 | MAPT (0.59) | ALDH1A1MAPTKDM4ELMNAPOLB | |
| SCHEMBL8356301 | 0.79 | MAPT (0.57) | ALDH1A1MAPTKDM4ELMNAPOLB | |
| SCHEMBL8354500 | 0.78 | MAPT (0.61) | ALDH1A1MAPTKDM4ELMNAPOLB | |
| SCHEMBL8356307 | 0.77 | MAPT (0.55) | ALDH1A1MAPTKDM4ELMNAPOLB | |
| SCHEMBL8357900 | 0.77 | MAPT (0.55) | ALDH1A1MAPTKDM4ELMNAPOLB | |
| SCHEMBL8358090 | 0.77 | MAPT (0.54) | ALDH1A1MAPTKDM4ELMNAPOLB | |
| SCHEMBL11261037 | 0.77 | MAPT (0.64) | ALDH1A1MAPTKDM4ELMNAPOLB | |
| SCHEMBL8353854 | 0.76 | ALDH1A1 (0.66) | ALDH1A1MAPTKDM4ELMNAPOLB | |
| SCHEMBL8353724 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4ELMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999031096-A1 | PIPERAZINE DERIVATIVES USEFUL AS HYPOGLYCEMIC AGENTS | SHAMAN PHARMACEUTICALS, INC. (US) | 1999-06-24 | — | — | WO | disclosed |