Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 6/20 | 1.00 |
| ▸ | FPR1 | P21462 | 1/20 | 0.83 |
| ▸ | CDK2 | P24941 | 1/20 | 0.83 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.72 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.72 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.59 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | USP7 | Q93009 | 1/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358260 | 0.92 | NR4A1 (0.85) | NR4A1FPR1CDK2HSPA1APTPN7 | |
| SCHEMBL8358146 | 0.91 | FPR1 (1.00) | NR4A1FPR1CDK2HSPA1APTPN7 | |
| SCHEMBL16325985 | 0.82 | NR4A1 (0.70) | NR4A1FPR1CDK2HSPA1APTPN7 | |
| SCHEMBL3413588 | 0.76 | NR4A1 (0.76) | NR4A1FPR1CDK2HSPA1APTPN7 | |
| SCHEMBL13856218 | 0.76 | NR4A1 (1.00) | NR4A1FPR1CDK2HSPA1APTPN7 | |
| SCHEMBL13856202 | 0.74 | NR4A1 (1.00) | NR4A1FPR1CDK2HSPA1APTPN7 | |
| SCHEMBL15828179 | 0.69 | NR4A1 (0.84) | NR4A1FPR1CDK2HSPA1APTPN7 | |
| SCHEMBL13856992 | 0.69 | NR4A1 (0.83) | NR4A1FPR1CDK2HSPA1APTPN7 | |
| SCHEMBL23949779 | 0.68 | NR4A1 (0.74) | NR4A1FPR1CDK2HSPA1APTPN7 | |
| SCHEMBL16406028 | 0.67 | USP7 (1.00) | NR4A1HSPA1APTPN7MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | THE BURNHAM INSTITUTE (US) | 2009-05-07 | — | — | US | disclosed |
| WO-2003039540-A2 | D-AMINO ACID OXIDASE INHIBITORS FOR LEARNING AND MEMORY | SEPRACOR INC. (US) | 2003-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | BCL2, BAX, BAD | NR4A1 4082/4885FPR1 4021/4885CDK2 263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.