SCHEMBL8358347

SCHEMBL8358347

CCCCCCCCOc1ccc(Cc2cccc(C(=O)c3ccccc3)c2O)cc1

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.50
TSHR P16473 1/20 0.50
PLA2G4B P0C869 6/20 0.49
PLK1 P53350 1/20 0.49
PTPN11 Q06124 2/20 0.47
RARB P10826 3/20 0.47
PPARG P37231 1/20 0.46
PLA2G4A P47712 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9303238 0.90 TP53 (0.53) TP53TSHRPLA2G4BPLK1PTPN11
SCHEMBL3820072 0.79 LMNA (0.58) TP53TSHRPTPN11
SCHEMBL2048120 0.79 LMNA (0.58) TP53TSHRPTPN11
SCHEMBL26097662 0.79 LMNA (0.58) TP53TSHRPTPN11
SCHEMBL28823845 0.79 BID (0.54) PPARG
SCHEMBL6648277 0.79 TP53 (0.73) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL534947 0.79 TP53 (0.73) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL11001285 0.79 TP53 (0.73) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL534753 0.79 TP53 (0.73) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL7921632 0.79 TP53 (0.73) TP53TSHRPLA2G4BRARBPLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0761788-B1 Protective film for polarizing plate KONISHIROKU PHOTO IND (JP) 1999-10-20 EP disclosed
US-5914073-A POLYMER COATING ON PLATE WITH ARYLATE MONOMERS IN FILM KONICA CORPORATION (JP) 1999-06-22 US disclosed
EP-0761788-A1 Protective film for polarizing plate KONICA CORPORATION (JP) 1997-03-12 EP disclosed