Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 11/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6607738 | 0.99 | DPP4 (0.45) | DPP4DPP7CYP1A2DPP8DPP9 | |
| SCHEMBL8361664 | 0.89 | DPP7 (0.57) | DPP4DPP7CYP1A2DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL4911332 | 0.88 | DPP7 (0.56) | DPP4DPP7CYP1A2DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL4911337 | 0.88 | DPP7 (0.56) | DPP4DPP7CYP1A2DPP8DPP9 | |
| SCHEMBL5872265 | 0.87 | DPP4 (0.54) | DPP4DPP7DPP8DPP9HDAC1 | |
| Hydrochloric Acid SCHEMBL5871551 | 0.86 | DPP4 (0.53) | DPP4DPP7DPP8DPP9HDAC1 | |
| SCHEMBL4907306 | 0.80 | TGM2 (0.41) | HDAC1 | |
| Hydrochloric Acid SCHEMBL6607735 | 0.73 | HDAC1 (0.37) | CYP1A2FAAHHDAC1HDAC2HDAC8 | |
| SCHEMBL5871953 | 0.71 | TGM2 (0.44) | DPP4DPP7DPP8DPP9HDAC1 | |
| SCHEMBL4915020 | 0.69 | TGM2 (0.42) | DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255126-A1 | Inhibitors of post-proline cleaving proteases | FERRING B.V. | 2008-10-16 | — | — | US | disclosed |
| US-20080255126-A1 | Inhibitors of post-proline cleaving proteases | FERRING B.V. | 2008-10-16 | — | — | US | disclosed |
| US-7335677-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING B.V. (NL) | 2008-02-26 | — | — | US | disclosed |
| US-7335677-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING B.V. (NL) | 2008-02-26 | — | — | US | disclosed |
| WO-2003035057-A1 | INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | FERRING B.V. (NL) | 2003-05-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255126-A1 | Inhibitors of post-proline cleaving proteases | PREP, PEPD, DPP4 | DPP4 3/4885DPP7 7/4885CYP1A2 1603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.