Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074318 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL8356350 | 0.75 | KDM4E (0.46) | KDM4EALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL10492171 | 0.75 | HSD17B10 (0.46) | KDM4EALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL1076963 | 0.72 | KDM4E (0.48) | KDM4EALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL4316072 | 0.67 | AXL (0.66) | KDM4EALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL11027233 | 0.66 | CA1 (0.48) | KDM4EALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL310518 | 0.66 | ALDH1A1 (0.47) | KDM4EALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL2439787 | 0.66 | ALDH1A1 (0.47) | KDM4EALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL29391519 | 0.65 | ALDH1A1 (1.00) | KDM4EALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL2597652 | 0.65 | ALDH1A1 (1.00) | KDM4EALDH1A1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877202-A | Indole derivatives useful to treat estrogen-related neoplasms and disorders | AVENTISUB II INC. | 1999-03-02 | — | — | US | disclosed |