Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 10/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.35 |
| ▸ | BIRC8 | Q96P09 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5832039 | 1.00 | XIAP (0.38) | XIAPACELMNACYP3A4TSHR | |
| SCHEMBL5832021 | 1.00 | XIAP (0.38) | XIAPACELMNACYP3A4TSHR | |
| SCHEMBL9609014 | 0.97 | ACE (0.40) | XIAPACECYP3A4TSHRTDP1 | |
| SCHEMBL26256186 | 0.97 | ACE (0.40) | XIAPACECYP3A4TSHRTDP1 | |
| SCHEMBL10331862 | 0.97 | ACE (0.40) | XIAPACECYP3A4TSHRTDP1 | |
| SCHEMBL12034318 | 0.97 | ACE (0.40) | XIAPACECYP3A4TSHRTDP1 | |
| SCHEMBL10331868 | 0.92 | ACE (0.43) | XIAPACELMNACYP3A4TSHR | |
| SCHEMBL7372848 | 0.92 | ACE (0.43) | XIAPACELMNACYP3A4TSHR | |
| SCHEMBL7372845 | 0.92 | ACE (0.43) | XIAPACELMNACYP3A4TSHR | |
| SCHEMBL10332106 | 0.92 | ACE (0.43) | XIAPACELMNACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106460-A1 | NOVEL INTERLEUKIN-1 BETA CONVERTING ENZYME INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2003-12-24 | — | — | WO | disclosed |