Tempol Hydroxylamine

Tempol Hydroxylamine

SCHEMBL8358933

CC1(C)CC(O)CC(C)(C)N1O.O=CO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 1/20 0.33
ALOX15 P16050 1/20 0.33
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tempol Hydroxylamine SCHEMBL23902 0.88 GAA (0.56) GAAL3MBTL1KDM4EALDH1A1ALOX15
Tempol Hydroxylamine SCHEMBL7099824 0.86 GAA (0.50) GAAL3MBTL1KDM4EALDH1A1ALOX15
Tempol Hydroxylamine SCHEMBL987556 0.85 GAA (0.54) GAAL3MBTL1KDM4EALDH1A1ALOX15
Tempol Hydroxylamine SCHEMBL986355 0.82 GAA (0.46) GAAL3MBTL1KDM4EALDH1A1ALOX15
Tempol Hydroxylamine SCHEMBL31285654 0.82 GAA (0.46) GAAL3MBTL1KDM4EALDH1A1ALOX15
Tempol Hydroxylamine SCHEMBL7526287 0.82 GAA (0.46) GAAL3MBTL1KDM4EALDH1A1ALOX15
Tempol Hydroxylamine SCHEMBL986308 0.82 GAA (0.46) GAAL3MBTL1KDM4EALDH1A1ALOX15
Tempol Hydroxylamine SCHEMBL7516297 0.82 GAA (0.46) GAAL3MBTL1KDM4EALDH1A1ALOX15
Tempol Hydroxylamine SCHEMBL3938500 0.77 GAA (0.46) GAAL3MBTL1
Tempol Hydroxylamine SCHEMBL28364622 0.77 GAA (0.42) GAAL3MBTL1KDM4EALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11263803-A None JP disclosed
JP-H11263803-A POLYMERIZATION TERMINATOR FOR VINYL POLYMERIZATION NALCO EXXON ENERG CHEM LP 1999-09-28 JP disclosed
EP-0927725-A2 Shortstop agents for vinyl polymerizations NALCO/EXXON ENERGY CHEMICALS, L.P. (US) 1999-07-07 EP disclosed
US-5880230-A ADDING COMPOUNDS CONTAINING OR CAPABLE OF FORMING A STABLE NITROXYL FREE RADICAL, SUCH AS 4-HYDROXY-2,2,6,6-TETRAMETHYL PIPERIDINE-1-OXYL; SYNTHETIC RUBBER PRODUCTION; NO NITROSAMINE PRECURSORS NALCO/EXXON ENERGY CHEMICALS, L.P. (US) 1999-03-09 US disclosed