Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.69 |
| ▸ | DRD1 | P21728 | 1/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.69 |
| ▸ | PDE4A | P27815 | 1/20 | 0.69 |
| ▸ | NPR1 | P16066 | 1/20 | 0.35 |
| ▸ | NPR3 | P17342 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.33 |
| ▸ | ITGAV | P06756 | 5/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | MC1R | Q01726 | 1/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354294 | 0.95 | CTSL (0.75) | CTSLDRD1PTGS1PDE4ANPR1 | |
| SCHEMBL8357546 | 0.95 | CTSL (0.75) | CTSLDRD1PTGS1PDE4ANPR1 | |
| SCHEMBL17253268 | 0.95 | CTSL (0.75) | CTSLDRD1PTGS1PDE4ANPR1 | |
| SCHEMBL8357548 | 0.94 | CTSL (0.70) | CTSLDRD1PTGS1PDE4ANPR1 | |
| SCHEMBL8226890 | 0.92 | CTSL (0.73) | CTSLDRD1PTGS1PDE4ANPR1 | |
| SCHEMBL8354165 | 0.90 | CTSL (0.73) | CTSLDRD1PTGS1PDE4ANPR1 | |
| SCHEMBL8242524 | 0.89 | CTSL (0.77) | CTSLDRD1PTGS1PDE4ANPR1 | |
| SCHEMBL8227164 | 0.88 | CTSL (0.69) | CTSLDRD1PTGS1PDE4ANPR1 | |
| SCHEMBL8221738 | 0.88 | CTSL (0.69) | CTSLDRD1PTGS1PDE4ANPR1 | |
| SCHEMBL12124851 | 0.87 | CTSL (0.70) | CTSLDRD1PTGS1PDE4ANPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003017924-A2 | LIPOPEPTIDE STEREOISOMERS, METHODS FOR PREPARING SAME, AND USEFUL INTERMEDIATES | CUBIST PHARMACEUTICALS, INC. (US) | 2003-03-06 | — | — | WO | disclosed |