Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8359264 | 1.00 | ERN1 (0.59) | ERN1KMT2AMAPTMEN1LMNA | |
| SCHEMBL1614148 | 0.85 | ERN1 (0.61) | ERN1KMT2AMAPTMEN1GAA | |
| SCHEMBL1450843 | 0.85 | ERN1 (0.61) | ERN1KMT2AMAPTMEN1GAA | |
| SCHEMBL27940191 | 0.83 | ERN1 (0.54) | ERN1KMT2AMAPTMEN1LMNA | |
| SCHEMBL25068364 | 0.83 | ERN1 (0.54) | ERN1KMT2AMAPTMEN1GAA | |
| SCHEMBL7915285 | 0.82 | ERN1 (0.70) | ERN1KMT2AMAPTMEN1GAA | |
| SCHEMBL7915280 | 0.82 | ERN1 (0.70) | ERN1KMT2AMAPTMEN1GAA | |
| SCHEMBL7523071 | 0.79 | ALDH1A1 (0.53) | ERN1KMT2AMAPTMEN1LMNA | |
| SCHEMBL2785457 | 0.79 | ALDH1A1 (0.53) | ERN1KMT2AMAPTMEN1LMNA | |
| SCHEMBL12714239 | 0.77 | APP (0.49) | ERN1KMT2AMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005151-A | Processs for preparing aromatic olefins using palladacycle catalysis | AVENTIS (DE) | 1999-12-21 | — | — | US | claimed |
| EP-0725049-A1 | Process for preparing aromatic olefins by palladacycle catalysis | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-07 | — | — | EP | claimed |
| US-6005151-A | Processs for preparing aromatic olefins using palladacycle catalysis | AVENTIS (DE) | 1999-12-21 | — | — | US | disclosed |