Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977110 | 0.80 | CYP2C19 (0.46) | CYP2C19SRCCYP2D6LMNAMAPK1 | |
| SCHEMBL11306355 | 0.80 | DPP4 (0.48) | CYP2C19SRCCYP2D6LMNAMAPK1 | |
| SCHEMBL8144421 | 0.79 | CYP2C19 (0.44) | CYP2C19SRCCYP2D6LMNAMAPK1 | |
| SCHEMBL622284 | 0.74 | CYP1A2 (0.57) | CYP2C19SRCCYP2D6LMNAMAPK1 | |
| SCHEMBL21119246 | 0.74 | CYP1A2 (0.57) | CYP2C19SRCCYP2D6LMNAMAPK1 | |
| SCHEMBL12833352 | 0.74 | CYP1A2 (0.57) | CYP2C19SRCCYP2D6LMNAMAPK1 | |
| SCHEMBL27976059 | 0.72 | CYP1A2 (0.55) | CYP2C19SRCCYP2D6LMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL10627471 | 0.72 | CYP1A2 (0.55) | CYP2C19SRCCYP2D6LMNAMAPK1 | |
| SCHEMBL23475220 | 0.72 | LMNA (0.59) | CYP2C19LMNACYP1A2HPGDHDAC1 | |
| SCHEMBL1742565 | 0.72 | SRC (0.59) | CYP2C19SRCCYP2D6LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999029640-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR | EISAI CO., LTD. (JP) | 1999-06-17 | — | — | WO | disclosed |